8jun: Difference between revisions
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New page: '''Unreleased structure''' The entry 8jun is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of SIDT1 E555Q mutant== | |||
<StructureSection load='8jun' size='340' side='right'caption='[[8jun]], [[Resolution|resolution]] 2.38Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8jun]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JUN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.38Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jun OCA], [https://pdbe.org/8jun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jun RCSB], [https://www.ebi.ac.uk/pdbsum/8jun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jun ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SIDT1_HUMAN SIDT1_HUMAN] In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded.[UniProtKB:Q6AXF6] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chen Y]] | |||
[[Category: Li Q]] | |||
[[Category: Sun CR]] | |||
[[Category: Xu D]] | |||
[[Category: Zhou CZ]] | |||
Latest revision as of 16:52, 24 January 2024
Cryo-EM structure of SIDT1 E555Q mutantCryo-EM structure of SIDT1 E555Q mutant
Structural highlights
FunctionSIDT1_HUMAN In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded.[UniProtKB:Q6AXF6] |
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