6ycs: Difference between revisions

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 <StructureSection load='6ycs' size='340' side='right'caption='[[6ycs]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6ycs]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YCS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6YCS FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6ycs]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YCS FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
-<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AS:2-DEOXY-ADENOSINE+-5-THIO-MONOPHOSPHATE'>AS</scene>, <scene name='pdbligand=GS:GUANOSINE-5-THIO-MONOPHOSPHATE'>GS</scene>, <scene name='pdbligand=OKN:'>OKN</scene>, <scene name='pdbligand=OKQ:'>OKQ</scene>, <scene name='pdbligand=OKT:'>OKT</scene>, <scene name='pdbligand=PST:THYMIDINE-5-THIOPHOSPHATE'>PST</scene>, <scene name='pdbligand=RFJ:'>RFJ</scene></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AS:2-DEOXY-ADENOSINE+-5-THIO-MONOPHOSPHATE'>AS</scene>, <scene name='pdbligand=GS:GUANOSINE-5-THIO-MONOPHOSPHATE'>GS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OKN:5-methyl-2-deoxycytidine-5-phosphorothioate'>OKN</scene>, <scene name='pdbligand=OKQ:2-O-methylcytidine-5-phosphorothioate'>OKQ</scene>, <scene name='pdbligand=OKT:2-O-methyluridine-5-phosphorothioate'>OKT</scene>, <scene name='pdbligand=PPS:3-PHOSPHATE-ADENOSINE-5-PHOSPHATE+SULFATE'>PPS</scene>, <scene name='pdbligand=PST:THYMIDINE-5-THIOPHOSPHATE'>PST</scene>, <scene name='pdbligand=RFJ:2-O-methyl-5-O-thiophosphonoguanosine'>RFJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PC4, SUB1, hCG_1781938 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ycs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ycs OCA], [https://pdbe.org/6ycs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ycs RCSB], [https://www.ebi.ac.uk/pdbsum/6ycs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ycs ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ycs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ycs OCA], [http://pdbe.org/6ycs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ycs RCSB], [http://www.ebi.ac.uk/pdbsum/6ycs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ycs ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/TCP4_HUMAN TCP4_HUMAN] General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).<ref>PMID:8062392</ref> <ref>PMID:8062391</ref> <ref>PMID:7628453</ref> <ref>PMID:9482861</ref> <ref>PMID:16689930</ref> <ref>PMID:9360603</ref> <ref>PMID:16605275</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 23: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Anderson, B]]
+[[Category: Synthetic construct]]
-[[Category: Crooke, S T]]
+[[Category: Anderson B]]
-[[Category: Hyjek-Skladanowska, M]]
+[[Category: Crooke ST]]
-[[Category: Liang, X]]
+[[Category: Hyjek-Skladanowska M]]
-[[Category: Napiorkowska, A]]
+[[Category: Liang X]]
-[[Category: Nowotny, M]]
+[[Category: Napiorkowska A]]
-[[Category: Seth, P P]]
+[[Category: Nowotny M]]
-[[Category: Tanowitz, M]]
+[[Category: Seth PP]]
-[[Category: Vickers, T A]]
+[[Category: Tanowitz M]]
-[[Category: 2'-o-methyl]]
+[[Category: Vickers TA]]
-[[Category: Aso]]
-[[Category: Dna binding]]
-[[Category: Phosphorothioate dna]]
-[[Category: Transcription]]