6tuc: Difference between revisions
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New page: '''Unreleased structure''' The entry 6tuc is ON HOLD until Paper Publication Authors: Sandner, A., Heine, A., Klebe, G. Description: Human Aldose Reductase in complex with ALR25 [[Cate... |
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==Human Aldose Reductase in complex with ALR25== | |||
<StructureSection load='6tuc' size='340' side='right'caption='[[6tuc]], [[Resolution|resolution]] 1.06Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6tuc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TUC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.06Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=NXK:2-(2-((3-boronobenzyl)carbamoyl)-5-fluorophenoxy)acetic+acid'>NXK</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tuc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tuc OCA], [https://pdbe.org/6tuc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tuc RCSB], [https://www.ebi.ac.uk/pdbsum/6tuc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tuc ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | |||
==See Also== | |||
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Heine | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Heine A]] | ||
[[Category: Klebe G]] | |||
[[Category: Sandner A]] | |||
Latest revision as of 16:09, 24 January 2024
Human Aldose Reductase in complex with ALR25Human Aldose Reductase in complex with ALR25
Structural highlights
FunctionALDR_HUMAN Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. See Also |
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