6ta2: Difference between revisions

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-'''Unreleased structure'''
-The entry 6ta2 is ON HOLD  until Paper Publication
+==Human NAMPT in complex with nicotinic acid mononucleotide and phosphate==
+<StructureSection load='6ta2' size='340' side='right'caption='[[6ta2]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ta2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TA2 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCN:NICOTINATE+MONONUCLEOTIDE'>NCN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ta2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ta2 OCA], [https://pdbe.org/6ta2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ta2 RCSB], [https://www.ebi.ac.uk/pdbsum/6ta2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ta2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NAMPT_HUMAN NAMPT_HUMAN] Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity).
-Authors: Houry, D., Raasakka, A., Kursula, P., Ziegler, M.
+==See Also==
+*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
-Description: Human NAMPT in complex with nicotinic acid mononucleotide and phosphate
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Houry, D]]
+[[Category: Homo sapiens]]
-[[Category: Kursula, P]]
+[[Category: Large Structures]]
-[[Category: Ziegler, M]]
+[[Category: Houry D]]
-[[Category: Raasakka, A]]
+[[Category: Kursula P]]
+[[Category: Raasakka A]]
+[[Category: Ziegler M]]