6t7k: Difference between revisions

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-'''Unreleased structure'''
-The entry 6t7k is ON HOLD  until Paper Publication
+==Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline==
+<StructureSection load='6t7k' size='340' side='right'caption='[[6t7k]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6t7k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T7K FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MU5:~{N}-(2,3-dihydro-1~{H}-inden-2-yl)-3-(piperidin-1-ylcarbonylamino)pyrazine-2-carboxamide'>MU5</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t7k OCA], [https://pdbe.org/6t7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t7k RCSB], [https://www.ebi.ac.uk/pdbsum/6t7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t7k ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SYP_PLAF7 SYP_PLAF7] Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity). Functions in trans to edit the amino acid moiety from incorrectly charged Ala-tRNA(Pro). Has no activity on correctly charged Pro-tRNA(Pro) or Ala-tRNA(Ala).<ref>PMID:14663147</ref>
-Authors: Johansson, C., Wang, J., Tye, M., Payne, N.C., Mazitschek, R., Thompson, A., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.C.T.
+==See Also==
+*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
-Description: Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Oppermann, U.C.T]]
+__TOC__
-[[Category: Arrowsmith, C.H]]
+</StructureSection>
-[[Category: Johansson, C]]
+[[Category: Large Structures]]
-[[Category: Tye, M]]
+[[Category: Plasmodium falciparum 3D7]]
-[[Category: Mazitschek, R]]
+[[Category: Arrowsmith CH]]
-[[Category: Edwards, A]]
+[[Category: Bountra C]]
-[[Category: Thompson, A]]
+[[Category: Edwards A]]
-[[Category: Payne, N.C]]
+[[Category: Johansson C]]
-[[Category: Wang, J]]
+[[Category: Mazitschek R]]
-[[Category: Bountra, C]]
+[[Category: Oppermann UCT]]
+[[Category: Payne NC]]
+[[Category: Thompson A]]
+[[Category: Tye M]]
+[[Category: Wang J]]