6rv3: Difference between revisions

<table><tr><td colspan='2'>[[6rv3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RV3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RV3 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMU:DECYL-BETA-D-MALTOPYRANOSIDE'>DMU</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=KKQ:[4-[[2-(4-bromophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]piperazin-1-yl]-(2-fluorophenyl)methanone'>KKQ</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KCNK3, TASK, TASK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rv3 OCA], [http://pdbe.org/6rv3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rv3 RCSB], [http://www.ebi.ac.uk/pdbsum/6rv3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rv3 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/KCNK3_HUMAN KCNK3_HUMAN]] Heritable pulmonary arterial hypertension. The disease is caused by mutations affecting the gene represented in this entry.  

[[http://www.uniprot.org/uniprot/KCNK3_HUMAN KCNK3_HUMAN]] pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.<ref>PMID:23169818</ref> <ref>PMID:9312005</ref>

[[Category: Human]]

[[Category: Arrowsmith, C H]]

[[Category: Bountra, C]]

[[Category: Burgess-Brown, N]]

[[Category: Bushell, S R]]

[[Category: Carpenter, E P]]

[[Category: Chalk, R]]

[[Category: Edwards, A M]]

[[Category: Mukhopadhyay, S M.M]]

[[Category: Pike, A C.W]]

[[Category: Quigley, A]]

[[Category: Rodstrom, K E.J]]

[[Category: Structural genomic]]

[[Category: Shrestha, L]]

[[Category: Speedman, D]]

[[Category: Tessitore, A]]

[[Category: Venkaya, S]]

[[Category: Zhang, W]]

[[Category: Sgc]]