6htt: Difference between revisions

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 ==Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 7==
-<StructureSection load='6htt' size='340' side='right' caption='[[6htt]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
+<StructureSection load='6htt' size='340' side='right'caption='[[6htt]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6htt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HTT FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6htt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HTT FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GQZ:~{N}1-oxidanyl-~{N}3-phenyl-benzene-1,3-dicarboxamide'>GQZ</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.748&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HDAC8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 Blood fluke])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMF:DIMETHYLFORMAMIDE'>DMF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GQZ:~{N}1-oxidanyl-~{N}3-phenyl-benzene-1,3-dicarboxamide'>GQZ</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6htt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6htt OCA], [https://pdbe.org/6htt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6htt RCSB], [https://www.ebi.ac.uk/pdbsum/6htt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6htt ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6htt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6htt OCA], [http://pdbe.org/6htt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6htt RCSB], [http://www.ebi.ac.uk/pdbsum/6htt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6htt ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/A5H660_SCHMA A5H660_SCHMA]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 18: / Line 19: @@
 </div>
 <div class="pdbe-citations 6htt" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Blood fluke]]
+[[Category: Large Structures]]
-[[Category: Histone deacetylase]]
+[[Category: Schistosoma mansoni]]
-[[Category: Marek, M]]
+[[Category: Marek M]]
-[[Category: Romier, C]]
+[[Category: Romier C]]
-[[Category: Shaik, T B]]
+[[Category: Shaik TB]]
-[[Category: Epigenetic]]
-[[Category: Hdac8]]
-[[Category: Hydrolase]]
-[[Category: Pathogen]]
-[[Category: Selective inhibitor]]