Salmeterol: Difference between revisions
New page: <StructureSection load='6mxt' size='340' side='right' caption='Caption for this structure' scene=''> Salmeterol (sold in China as Qitai[2]) is a long-acting β2 adrenergic receptor agonist... |
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<StructureSection load=' | <StructureSection load='' size='340' side='right' caption='Salmeterol' scene='95/955176/Cv/1'> | ||
Salmeterol | Salmeterol is a long-acting β2 adrenergic receptor agonist (LABA) used in the maintenance and prevention of asthma symptoms and maintenance of chronic obstructive pulmonary disease (COPD) symptoms. See also [https://en.wikipedia.org/wiki/Salmeterol]. | ||
Inhaled salmeterol belongs to a group of drugs called beta-2 agonists. These drugs stimulate [[beta-2 receptors]] present in the bronchial musculature. This causes them to relax and prevent the onset and worsening of symptoms of asthma. They act on the enzyme [[adenyl cyclase]] which increases the concentration of cAMP (Cyclic adenosine monophosphate). This cyclic AMP decreases the smooth muscle tone. This drug is 10,000-times more lipid soluble than the short acting beta-2 adrenoceptor agonist, albuterol. Unlike albuterol, salmeterol becomes dissolved in the lipid bilayer of the cell membrane, and its gradual dissociation from the cell membrane provides beta-2 adrenoceptors with a supply of agonist for an extended period of time. | |||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||