5nw7: Difference between revisions
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==Crystal structure of candida albicans phosphomannose isomerase in complex with inhibitor== | ==Crystal structure of candida albicans phosphomannose isomerase in complex with inhibitor== | ||
<StructureSection load='5nw7' size='340' side='right' caption='[[5nw7]], [[Resolution|resolution]] 1.85Å' scene=''> | <StructureSection load='5nw7' size='340' side='right'caption='[[5nw7]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5nw7]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5nw7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NW7 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9C2:[(2~{R},3~{R},4~{S})-5-diazanyl-2,3,4-tris(oxidanyl)-5-oxidanylidene-pentyl]+dihydrogen+phosphate'>9C2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9C2:[(2~{R},3~{R},4~{S})-5-diazanyl-2,3,4-tris(oxidanyl)-5-oxidanylidene-pentyl]+dihydrogen+phosphate'>9C2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nw7 OCA], [https://pdbe.org/5nw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nw7 RCSB], [https://www.ebi.ac.uk/pdbsum/5nw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nw7 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MPI_CANAL MPI_CANAL] Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Candida albicans]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Ahmad L]] | ||
[[Category: Li de la Sierra-Gallay I]] | |||
[[Category: Sierra-Gallay | [[Category: Plancqueel S]] | ||
[[Category: | [[Category: Salmon L]] | ||
[[Category: | [[Category: Van Tilbeurgh H]] | ||
[[Category: | |||