5eww: Difference between revisions

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-'''Unreleased structure'''
-The entry 5eww is ON HOLD  until Paper Publication
+==Crystal structure of the human BRPF1 bromodomain in complex with SEED21==
+<StructureSection load='5eww' size='340' side='right'caption='[[5eww]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5eww]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EWW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EWW FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5SK:~{N}-[(2~{R})-BUTAN-2-YL]-1-METHYL-[1,2,4]TRIAZOLO[4,3-A]QUINOXALIN-4-AMINE'>5SK</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eww OCA], [https://pdbe.org/5eww PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eww RCSB], [https://www.ebi.ac.uk/pdbsum/5eww PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eww ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>
-Authors: Zhu, J., Caflisch, A.
+==See Also==
+*[[Peregrin|Peregrin]]
-Description: Crystal structure of the human BRPF1 bromodomain in complex with SEED21
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Caflisch, A]]
+__TOC__
-[[Category: Zhu, J]]
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Caflisch A]]
+[[Category: Wiedmer L]]
+[[Category: Zhu J]]