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==Structure of the human glucose transporter GLUT3 / SLC2A3==
==Structure of the human glucose transporter GLUT3 / SLC2A3==
<StructureSection load='5c65' size='340' side='right' caption='[[5c65]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='5c65' size='340' side='right'caption='[[5c65]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5c65]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C65 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C65 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5c65]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C65 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=37X:OCTYL+GLUCOSE+NEOPENTYL+GLYCOL'>37X</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c65 OCA], [http://pdbe.org/5c65 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c65 RCSB], [http://www.ebi.ac.uk/pdbsum/5c65 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c65 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=37X:OCTYL+GLUCOSE+NEOPENTYL+GLYCOL'>37X</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c65 OCA], [https://pdbe.org/5c65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c65 RCSB], [https://www.ebi.ac.uk/pdbsum/5c65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c65 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/GTR3_HUMAN GTR3_HUMAN]] Huntington disease.
[https://www.uniprot.org/uniprot/GTR3_HUMAN GTR3_HUMAN] Huntington disease.  
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GTR3_HUMAN GTR3_HUMAN]] Facilitative glucose transporter. Probably a neuronal glucose transporter.  
[https://www.uniprot.org/uniprot/GTR3_HUMAN GTR3_HUMAN] Facilitative glucose transporter. Probably a neuronal glucose transporter.
 
==See Also==
*[[Glut3|Glut3]]
*[[Sanbox glut3|Sanbox glut3]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Homo sapiens]]
[[Category: Bountra, C]]
[[Category: Large Structures]]
[[Category: Burgess-Brown, N A]]
[[Category: Arrowsmith CH]]
[[Category: Carpenter, E P]]
[[Category: Bountra C]]
[[Category: Chalk, R]]
[[Category: Burgess-Brown NA]]
[[Category: Chu, A]]
[[Category: Carpenter EP]]
[[Category: Edwards, A M]]
[[Category: Chalk R]]
[[Category: Kupinska, K]]
[[Category: Chu A]]
[[Category: Mukhopadhyay, S]]
[[Category: Edwards AM]]
[[Category: Pike, A C.W]]
[[Category: Kupinska K]]
[[Category: Quigley, A]]
[[Category: Mukhopadhyay S]]
[[Category: Structural genomic]]
[[Category: Pike ACW]]
[[Category: Strain-Damerell, C]]
[[Category: Quigley A]]
[[Category: Tessitore, A]]
[[Category: Strain-Damerell C]]
[[Category: Wang, D]]
[[Category: Tessitore A]]
[[Category: Xia, X]]
[[Category: Wang D]]
[[Category: Membrane transporter]]
[[Category: Xia X]]
[[Category: Sgc]]
[[Category: Sugar transport]]
[[Category: Transport protein]]

Latest revision as of 14:18, 10 January 2024

Structure of the human glucose transporter GLUT3 / SLC2A3Structure of the human glucose transporter GLUT3 / SLC2A3

Structural highlights

5c65 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.65Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

GTR3_HUMAN Huntington disease.

Function

GTR3_HUMAN Facilitative glucose transporter. Probably a neuronal glucose transporter.

5c65, resolution 2.65Å

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