5bp4: Difference between revisions

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{{Large structure}}
 
==Modifying region (DH-ER-KR) of the mycocerosic acid synthase (MAS)==
==Modifying region (DH-ER-KR) of a mycocerosic acid synthase-like (MAS-like) PKS==
<StructureSection load='5bp4' size='340' side='right' caption='[[5bp4]], [[Resolution|resolution]] 3.75&Aring;' scene=''>
<StructureSection load='5bp4' size='340' side='right'caption='[[5bp4]], [[Resolution|resolution]] 3.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5bp4]] is a 18 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BP4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5bp4]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BP4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.75&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bp2|5bp2]], [[5bp3|5bp3]], [[5bp5|5bp5]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mycocerosate_synthase Mycocerosate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.111 2.3.1.111] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bp4 OCA], [https://pdbe.org/5bp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bp4 RCSB], [https://www.ebi.ac.uk/pdbsum/5bp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bp4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bp4 OCA], [http://pdbe.org/5bp4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bp4 RCSB], [http://www.ebi.ac.uk/pdbsum/5bp4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bp4 ProSAT]</span></td></tr>
</table>
</table>
{{Large structure}}
== Function ==
[https://www.uniprot.org/uniprot/PKS5_MYCS2 PKS5_MYCS2] Polyketide synthase involved in the biosynthesis of 2,4-dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis.<ref>PMID:19181796</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Mycocerosate synthase]]
[[Category: Large Structures]]
[[Category: Herbst, D A]]
[[Category: Mycolicibacterium smegmatis MC2 155]]
[[Category: Jakob, P R]]
[[Category: Herbst DA]]
[[Category: Maier, T]]
[[Category: Jakob PR]]
[[Category: Zaehringer, F]]
[[Category: Maier T]]
[[Category: Dehydratase]]
[[Category: Zaehringer F]]
[[Category: Enoylreductase]]
[[Category: Ketoreductase]]
[[Category: Polyketide]]
[[Category: Transferase]]

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