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==Crystal structure of JmjC domain of human histone demethylase UTY with S21056a==
==Crystal structure of JmjC domain of human histone demethylase UTY with S21056a==
<StructureSection load='5a1l' size='340' side='right' caption='[[5a1l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='5a1l' size='340' side='right'caption='[[5a1l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5a1l]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A1L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A1L FirstGlance]. <br>
<table><tr><td colspan='2'>[[5a1l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A1L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A1L FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=S2I:3-[[2-PYRIDIN-2-YL-6-(1,2,4,5-TETRAHYDRO-3-BENZAZEPIN-3-YL)PYRIMIDIN-4-YL]AMINO]PROPAN-1-OL'>S2I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a1l OCA], [http://pdbe.org/5a1l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a1l RCSB], [http://www.ebi.ac.uk/pdbsum/5a1l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a1l ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=S2I:3-[[2-PYRIDIN-2-YL-6-(1,2,4,5-TETRAHYDRO-3-BENZAZEPIN-3-YL)PYRIMIDIN-4-YL]AMINO]PROPAN-1-OL'>S2I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a1l OCA], [https://pdbe.org/5a1l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a1l RCSB], [https://www.ebi.ac.uk/pdbsum/5a1l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a1l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN] Histone demethylase (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Homo sapiens]]
[[Category: Bountra, C]]
[[Category: Large Structures]]
[[Category: Brennan, P]]
[[Category: Arrowsmith CH]]
[[Category: Delft, F von]]
[[Category: Bountra C]]
[[Category: Edwards, A]]
[[Category: Brennan P]]
[[Category: Gileadi, C]]
[[Category: Edwards A]]
[[Category: Johansson, C]]
[[Category: Gileadi C]]
[[Category: Krojer, T]]
[[Category: Johansson C]]
[[Category: Oppermann, U]]
[[Category: Krojer T]]
[[Category: Srikannathasan, V]]
[[Category: Oppermann U]]
[[Category: Tumber, A]]
[[Category: Srikannathasan V]]
[[Category: Hydrolase]]
[[Category: Tumber A]]
[[Category: Von Delft F]]

Latest revision as of 14:02, 10 January 2024

Crystal structure of JmjC domain of human histone demethylase UTY with S21056aCrystal structure of JmjC domain of human histone demethylase UTY with S21056a

Structural highlights

5a1l is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UTY_HUMAN Histone demethylase (By similarity).

5a1l, resolution 2.00Å

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