4y62: Difference between revisions
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New page: '''Unreleased structure''' The entry 4y62 is ON HOLD until Paper Publication Authors: Wang, S., Cuesta-Seijo, J.A., Striebeck, A., Lafont, D., Palcic, M.M., Vidal, S. Description: [[C... |
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==AAGlyB in complex with amino-acid analogues== | |||
<StructureSection load='4y62' size='340' side='right'caption='[[4y62]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4y62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y62 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=48E:5-DEOXY-5-{[(2R)-3-HYDROXY-2-(4-PHENYL-1H-1,2,3-TRIAZOL-1-YL)PROPANOYL]AMINO}URIDINE'>48E</scene>, <scene name='pdbligand=BHE:OCTYL+2-O-(6-DEOXY-ALPHA-L-GALACTOPYRANOSYL)-BETA-D-GALACTOPYRANOSIDE'>BHE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y62 OCA], [https://pdbe.org/4y62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y62 RCSB], [https://www.ebi.ac.uk/pdbsum/4y62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y62 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | |||
==See Also== | |||
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Cuesta-Seijo | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Cuesta-Seijo JA]] | ||
[[Category: | [[Category: Lafont D]] | ||
[[Category: Vidal | [[Category: Palcic MM]] | ||
[[Category: | [[Category: Striebeck A]] | ||
[[Category: Vidal S]] | |||
[[Category: Wang S]] | |||
Latest revision as of 13:53, 10 January 2024
AAGlyB in complex with amino-acid analoguesAAGlyB in complex with amino-acid analogues
Structural highlights
FunctionBGAT_HUMAN This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. See Also |
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