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==Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 8.0 with MPD as the cryoprotectant==
==Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 8.0 with MPD as the cryoprotectant==
<StructureSection load='4xio' size='340' side='right' caption='[[4xio]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4xio' size='340' side='right'caption='[[4xio]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4xio]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XIO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4xio]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XIO FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xio OCA], [http://pdbe.org/4xio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xio RCSB], [http://www.ebi.ac.uk/pdbsum/4xio PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xio OCA], [https://pdbe.org/4xio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xio RCSB], [https://www.ebi.ac.uk/pdbsum/4xio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xio ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NANB_STRPN NANB_STRPN]
==See Also==
*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Exo-alpha-sialidase]]
[[Category: Large Structures]]
[[Category: Brear, P]]
[[Category: Streptococcus pneumoniae TIGR4]]
[[Category: Allosteric inhibitor]]
[[Category: Brear P]]
[[Category: Crystallization artefact]]
[[Category: Drug design]]
[[Category: Glycosidase]]
[[Category: Hydrolase]]
[[Category: Intramolecular trans-sialidase]]
[[Category: Neuraminidase]]
[[Category: Serendipitous allosteric site]]

Latest revision as of 13:48, 10 January 2024

Crystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 8.0 with MPD as the cryoprotectantCrystal structure of apo NanB sialidase from streptococcus pneumoniae at pH 8.0 with MPD as the cryoprotectant

Structural highlights

4xio is a 1 chain structure with sequence from Streptococcus pneumoniae TIGR4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NANB_STRPN

See Also

4xio, resolution 1.80Å

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