4v2s: Difference between revisions

<StructureSection load='4v2s' size='340' side='right'caption='[[4v2s]], [[Resolution|resolution]] 3.48&Aring;' scene=''>

<table><tr><td colspan='2'>[[4v2s]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V2S FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.48&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v2s OCA], [https://pdbe.org/4v2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v2s RCSB], [https://www.ebi.ac.uk/pdbsum/4v2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v2s ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/HFQ_ECOLI HFQ_ECOLI] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Involved in the regulation of stress responses mediated by the sigma factors RpoS, sigma-E and sigma-32. Binds with high specificity to tRNAs. In vitro, stimulates synthesis of long tails by poly(A) polymerase I. Required for RNA phage Qbeta replication.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>  Seems to play a role in persister cell formation; upon overexpression decreases persister cell formation while deletion increases persister formation.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>  

[[Category: Escherichia coli K-12]]

[[Category: Large Structures]]

[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]

[[Category: Bandyra KJ]]

[[Category: Bruce HA]]

[[Category: Dimastrogiovanni D]]

[[Category: Frohlich KS]]

[[Category: Hohensee S]]

[[Category: Luisi BF]]

[[Category: Vogel J]]