4uuv: Difference between revisions
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==Structure of the DNA binding ETS domain of human ETV4 in complex with DNA== | ==Structure of the DNA binding ETS domain of human ETV4 in complex with DNA== | ||
<StructureSection load='4uuv' size='340' side='right' caption='[[4uuv]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='4uuv' size='340' side='right'caption='[[4uuv]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4uuv]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UUV OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4uuv]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UUV FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uuv OCA], [https://pdbe.org/4uuv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uuv RCSB], [https://www.ebi.ac.uk/pdbsum/4uuv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uuv ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN] Ewing sarcoma. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN] Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.<ref>PMID:19307308</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Synthetic construct]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: Edwards | [[Category: Bountra C]] | ||
[[Category: Gileadi | [[Category: Cooper CDO]] | ||
[[Category: Kopec | [[Category: Edwards AM]] | ||
[[Category: Newman | [[Category: Gileadi O]] | ||
[[Category: | [[Category: Kopec J]] | ||
[[Category: Newman JA]] | |||
[[Category: Von Delft F]] | |||