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==Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens==
==Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens==
<StructureSection load='4utt' size='340' side='right' caption='[[4utt]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
<StructureSection load='4utt' size='340' side='right'caption='[[4utt]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4utt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UTT FirstGlance]. <br>
<table><tr><td colspan='2'>[[4utt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens_str._13 Clostridium perfringens str. 13]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UTT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4utu|4utu]], [[4utw|4utw]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylglucosamine-6-phosphate_2-epimerase N-acylglucosamine-6-phosphate 2-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.9 5.1.3.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4utt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4utt OCA], [https://pdbe.org/4utt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4utt RCSB], [https://www.ebi.ac.uk/pdbsum/4utt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4utt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4utt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4utt OCA], [http://pdbe.org/4utt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4utt RCSB], [http://www.ebi.ac.uk/pdbsum/4utt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4utt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NANE_CLOP1 NANE_CLOP1]] Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).  
[https://www.uniprot.org/uniprot/NANE_CLOPE NANE_CLOPE] Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: N-acylglucosamine-6-phosphate 2-epimerase]]
[[Category: Clostridium perfringens str. 13]]
[[Category: Bourne, Y]]
[[Category: Large Structures]]
[[Category: Brannigan, J A]]
[[Category: Bourne Y]]
[[Category: Davies, G J]]
[[Category: Brannigan JA]]
[[Category: Guerlesquin, F]]
[[Category: Davies GJ]]
[[Category: Pelissier, M C]]
[[Category: Guerlesquin F]]
[[Category: Sebban-Kreuzer, C]]
[[Category: Pelissier MC]]
[[Category: Vincent, F]]
[[Category: Sebban-Kreuzer C]]
[[Category: 1h nmr spectroscopy]]
[[Category: Vincent F]]
[[Category: Carbohydrate]]
[[Category: Enzyme mechanism]]
[[Category: Isomerase]]
[[Category: Mutagenesis]]
[[Category: Sialic acid]]
[[Category: Sugar 2-epimerase]]
[[Category: Sugar phosphate]]

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