8hxr: Difference between revisions

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-'''Unreleased structure'''
-The entry 8hxr is ON HOLD
+==Nanobody2 in complex with human BCMA ECD==
+<StructureSection load='8hxr' size='340' side='right'caption='[[8hxr]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-Authors: Yan, S., Bing, Z.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8hxr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HXR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HXR FirstGlance]. <br>
-Description: Nanobody2 in complex with human BCMA ECD
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hxr OCA], [https://pdbe.org/8hxr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hxr RCSB], [https://www.ebi.ac.uk/pdbsum/8hxr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hxr ProSAT]</span></td></tr>
-[[Category: Bing, Z]]
+</table>
-[[Category: Yan, S]]
+== Disease ==
+[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
+== Function ==
+[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.<ref>PMID:10903733</ref> <ref>PMID:10801128</ref> <ref>PMID:10973284</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Vicugna pacos]]
+[[Category: Sun Y]]
+[[Category: Zhang B]]