8br9: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[8br9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BR9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[8br9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BR9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=RF6:4,6-diethylpyrimidin-2-amine'>RF6</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=RF6:4,6-diethylpyrimidin-2-amine'>RF6</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8br9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8br9 OCA], [https://pdbe.org/8br9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8br9 RCSB], [https://www.ebi.ac.uk/pdbsum/8br9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8br9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8br9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8br9 OCA], [https://pdbe.org/8br9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8br9 RCSB], [https://www.ebi.ac.uk/pdbsum/8br9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8br9 ProSAT]</span></td></tr>
</table>
</table>

Latest revision as of 03:57, 28 December 2023

Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22

Structural highlights

8br9 is a 2 chain structure with sequence from Homo sapiens and Pyrococcus furiosus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.63Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RADA_PYRFU Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

8br9, resolution 1.63Å

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