4wf8: Difference between revisions

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OCA

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 ==Crystal structure of NS3/4A protease in complex with Asunaprevir==
-<StructureSection load='4wf8' size='340' side='right' caption='[[4wf8]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+<StructureSection load='4wf8' size='340' side='right'caption='[[4wf8]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4wf8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WF8 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4wf8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WF8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WF8 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2R9:N-(TERT-BUTOXYCARBONYL)-3-METHYL-L-VALYL-(4R)-4-[(7-CHLORO-4-METHOXYISOQUINOLIN-1-YL)OXY]-N-{(1R,2S)-1-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-ETHENYLCYCLOPROPYL}-L-PROLINAMIDE'>2R9</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wf8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wf8 RCSB], [http://www.ebi.ac.uk/pdbsum/4wf8 PDBsum]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2R9:N-(TERT-BUTOXYCARBONYL)-3-METHYL-L-VALYL-(4R)-4-[(7-CHLORO-4-METHOXYISOQUINOLIN-1-YL)OXY]-N-{(1R,2S)-1-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-ETHENYLCYCLOPROPYL}-L-PROLINAMIDE'>2R9</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wf8 OCA], [https://pdbe.org/4wf8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wf8 RCSB], [https://www.ebi.ac.uk/pdbsum/4wf8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wf8 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/X2G809_9HEPC X2G809_9HEPC]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 14: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4wf8" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Virus protease 3D structures|Virus protease 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Ali, A]]
+[[Category: Hepacivirus C]]
-[[Category: Schiffer, C A]]
+[[Category: Large Structures]]
-[[Category: Soumana, D I]]
+[[Category: Ali A]]
-[[Category: Hcv protease inhibitor complex]]
+[[Category: Schiffer CA]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Soumana DI]]
-[[Category: Resistance]]