4pii: Difference between revisions

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 ==Crystal structure of hypothetical protein PF0907 from pyrococcus furiosus solved by sulfur SAD using Swiss light source data==
-<StructureSection load='4pii' size='340' side='right' caption='[[4pii]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
+<StructureSection load='4pii' size='340' side='right'caption='[[4pii]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4pii]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PII FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4pii]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PII FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xg7|1xg7]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pii OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pii RCSB], [http://www.ebi.ac.uk/pdbsum/4pii PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pii OCA], [https://pdbe.org/4pii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pii RCSB], [https://www.ebi.ac.uk/pdbsum/4pii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pii ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/AGOG_PYRFU AGOG_PYRFU] DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates (By similarity).
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+We describe a data collection method that uses a single crystal to solve X-ray structures by native SAD (single-wavelength anomalous diffraction). We solved the structures of 11 real-life examples, including a human membrane protein, a protein-DNA complex and a 266-kDa multiprotein-ligand complex, using this method. The data collection strategy is suitable for routine structure determination and can be implemented at most macromolecular crystallography synchrotron beamlines.
+Fast native-SAD phasing for routine macromolecular structure determination.,Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, Zhou D, Rose J, Ebihara A, Kuramitsu S, Li D, Howe N, Schnapp G, Pautsch A, Bargsten K, Prota AE, Surana P, Kottur J, Nair DT, Basilico F, Cecatiello V, Pasqualato S, Boland A, Weichenrieder O, Wang B, Steinmetz MO, Caffrey M, Wang M Nat Methods. 2014 Dec 15. doi: 10.1038/nmeth.3211. PMID:25506719<ref>PMID:25506719</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 4pii" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
-[[Category: Chen, L]]
+[[Category: Large Structures]]
-[[Category: Olieric, V]]
+[[Category: Pyrococcus furiosus DSM 3638]]
-[[Category: Panepucci, E]]
+[[Category: Chen L]]
-[[Category: Rose, J P]]
+[[Category: Olieric V]]
-[[Category: Structural genomic]]
+[[Category: Panepucci E]]
-[[Category: Waltersperger, S]]
+[[Category: Rose JP]]
-[[Category: Wang, B C]]
+[[Category: Waltersperger S]]
-[[Category: Wang, M]]
+[[Category: Wang BC]]
-[[Category: Weinert, T]]
+[[Category: Wang M]]
-[[Category: Sulfur sad]]
+[[Category: Weinert T]]
-[[Category: Unknown function]]