4owp: Difference between revisions

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'''Unreleased structure'''


The entry 4owp is ON HOLD  until Aug 03 2016
==Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.==
<StructureSection load='4owp' size='340' side='right'caption='[[4owp]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4owp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OWP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4owp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4owp OCA], [https://pdbe.org/4owp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4owp RCSB], [https://www.ebi.ac.uk/pdbsum/4owp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4owp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPN8_YEAST RPN8_YEAST] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:9584156</ref>


Authors: Yu, Z., Mansour, W., Nakasone, M.A., Glickman, M.H., Dvir, H.
==See Also==
 
*[[Proteasome 3D structures|Proteasome 3D structures]]
Description: Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteosome lid.
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Dvir H]]
[[Category: Glickman MH]]
[[Category: Mansour W]]
[[Category: Nakasone MA]]
[[Category: Yu Z]]

Latest revision as of 03:37, 28 December 2023

Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.

Structural highlights

4owp is a 2 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.35Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RPN8_YEAST Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[1]

See Also

References

  1. ↑ Glickman MH, Rubin DM, Fried VA, Finley D. The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol. 1998 Jun;18(6):3149-62. PMID:9584156

4owp, resolution 2.35Å

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