3npe: Difference between revisions

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==Structure of VP14 in complex with oxygen==
==Structure of VP14 in complex with oxygen==
<StructureSection load='3npe' size='340' side='right' caption='[[3npe]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='3npe' size='340' side='right'caption='[[3npe]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3npe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NPE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NPE FirstGlance]. <br>
<table><tr><td colspan='2'>[[3npe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NPE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/9-cis-epoxycarotenoid_dioxygenase 9-cis-epoxycarotenoid dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.51 1.13.11.51] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3npe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3npe OCA], [http://pdbe.org/3npe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3npe RCSB], [http://www.ebi.ac.uk/pdbsum/3npe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3npe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3npe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3npe OCA], [https://pdbe.org/3npe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3npe RCSB], [https://www.ebi.ac.uk/pdbsum/3npe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3npe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NCED1_MAIZE NCED1_MAIZE]] Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids. Not active on the all-trans isomers of violaxanthin and neoxanthin. Contributes probably to abscisic acid synthesis for the induction of seed dormancy.<ref>PMID:9342392</ref> <ref>PMID:9188535</ref> <ref>PMID:20884803</ref>
[https://www.uniprot.org/uniprot/NCED1_MAIZE NCED1_MAIZE] Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids. Not active on the all-trans isomers of violaxanthin and neoxanthin. Contributes probably to abscisic acid synthesis for the induction of seed dormancy.<ref>PMID:9342392</ref> <ref>PMID:9188535</ref> <ref>PMID:20884803</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 9-cis-epoxycarotenoid dioxygenase]]
[[Category: Large Structures]]
[[Category: Amzel, L M]]
[[Category: Zea mays]]
[[Category: Gabelli, S B]]
[[Category: Amzel LM]]
[[Category: Messing, S A]]
[[Category: Gabelli SB]]
[[Category: Abscisic acid]]
[[Category: Messing SA]]
[[Category: Dioxygenase]]
[[Category: Non heme iron]]
[[Category: Oxidoreductase]]
[[Category: Seven blade beta propeller]]

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