3f31: Difference between revisions
No edit summary |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal Structure of the N-terminal region of AlphaII-spectrin Tetramerization Domain== | ==Crystal Structure of the N-terminal region of AlphaII-spectrin Tetramerization Domain== | ||
<StructureSection load='3f31' size='340' side='right' caption='[[3f31]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='3f31' size='340' side='right'caption='[[3f31]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3f31]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3f31]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F31 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F31 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f31 OCA], [https://pdbe.org/3f31 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f31 RCSB], [https://www.ebi.ac.uk/pdbsum/3f31 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f31 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] West syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f3/3f31_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f3/3f31_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 31: | Line 30: | ||
</div> | </div> | ||
<div class="pdbe-citations 3f31" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3f31" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Spectrin 3D structures|Spectrin 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Fung | [[Category: Large Structures]] | ||
[[Category: Long | [[Category: Fung LW]] | ||
[[Category: Mehboob | [[Category: Long F]] | ||
[[Category: Santarsiero | [[Category: Mehboob S]] | ||
[[Category: Witek | [[Category: Santarsiero BD]] | ||
[[Category: Witek M]] | |||