3f1c: Difference between revisions

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==CRYSTAL STRUCTURE OF 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Listeria monocytogenes==
==CRYSTAL STRUCTURE OF 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Listeria monocytogenes==
<StructureSection load='3f1c' size='340' side='right' caption='[[3f1c]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3f1c' size='340' side='right'caption='[[3f1c]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3f1c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lismf Lismf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F1C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F1C FirstGlance]. <br>
<table><tr><td colspan='2'>[[3f1c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_serotype_4b_str._F2365 Listeria monocytogenes serotype 4b str. F2365]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F1C FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispD2, LMOf2365_1100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=265669 LISMF])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f1c OCA], [https://pdbe.org/3f1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f1c RCSB], [https://www.ebi.ac.uk/pdbsum/3f1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f1c ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3f1c TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f1c OCA], [http://pdbe.org/3f1c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3f1c RCSB], [http://www.ebi.ac.uk/pdbsum/3f1c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3f1c ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/3f1c TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ISPD2_LISMF ISPD2_LISMF]] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).  
[https://www.uniprot.org/uniprot/TARI_LISMF TARI_LISMF] Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.[HAMAP-Rule:MF_02068]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f1/3f1c_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f1/3f1c_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
[[Category: Large Structures]]
[[Category: Lismf]]
[[Category: Listeria monocytogenes serotype 4b str. F2365]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Gilmore, M]]
[[Category: Gilmore M]]
[[Category: Groshong, C]]
[[Category: Groshong C]]
[[Category: Ho, J]]
[[Category: Ho J]]
[[Category: Miller, S]]
[[Category: Miller S]]
[[Category: Structural genomic]]
[[Category: Patskovsky Y]]
[[Category: Patskovsky, Y]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: Toro R]]
[[Category: Toro, R]]
[[Category: Isoprene biosynthesis]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Nucleotidyltransferase]]
[[Category: PSI, Protein structure initiative]]
[[Category: Transferase]]

Latest revision as of 03:27, 28 December 2023

CRYSTAL STRUCTURE OF 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Listeria monocytogenesCRYSTAL STRUCTURE OF 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Listeria monocytogenes

Structural highlights

3f1c is a 2 chain structure with sequence from Listeria monocytogenes serotype 4b str. F2365. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

TARI_LISMF Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.[HAMAP-Rule:MF_02068]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3f1c, resolution 2.30Å

Drag the structure with the mouse to rotate

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OCA