3erq: Difference between revisions

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[[Image:3erq.png|left|200px]]


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==Crystal structure of Staphylococcal nuclease variant L25K at cryogenic temperature==
The line below this paragraph, containing "STRUCTURE_3erq", creates the "Structure Box" on the page.
<StructureSection load='3erq' size='340' side='right'caption='[[3erq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3erq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ERQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ERQ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
{{STRUCTURE_3erq| PDB=3erq |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3erq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3erq OCA], [https://pdbe.org/3erq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3erq RCSB], [https://www.ebi.ac.uk/pdbsum/3erq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3erq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/er/3erq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3erq ConSurf].
<div style="clear:both"></div>


===Crystal structure of Staphylococcal nuclease variant L25K at cryogenic temperature===
==See Also==
 
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3erq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ERQ OCA].
[[Category: Large Structures]]
[[Category: Micrococcal nuclease]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Garcia-Moreno, E B.]]
[[Category: Garcia-Moreno EB]]
[[Category: Robinson, A C.]]
[[Category: Robinson AC]]
[[Category: Schlessman, J L.]]
[[Category: Schlessman JL]]
[[Category: Endonuclease]]
[[Category: Hydrolase]]
[[Category: Hyperstable variant]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Nuclease]]
[[Category: Pdtp]]
[[Category: Secreted]]
[[Category: Staphylococcal nuclease]]
[[Category: Zymogen]]

Latest revision as of 03:23, 28 December 2023

Crystal structure of Staphylococcal nuclease variant L25K at cryogenic temperatureCrystal structure of Staphylococcal nuclease variant L25K at cryogenic temperature

Structural highlights

3erq is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUC_STAAU Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3erq, resolution 2.10Å

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OCA