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==Crystal structure of protein LPL1258 from Legionella pneumophila str. Philadelphia 1, Pfam DUF519==
==Crystal structure of protein LPL1258 from Legionella pneumophila str. Philadelphia 1, Pfam DUF519==
<StructureSection load='2oo3' size='340' side='right' caption='[[2oo3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2oo3' size='340' side='right'caption='[[2oo3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2oo3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila Legionella pneumophila subsp. pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OO3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2oo3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila Legionella pneumophila subsp. pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OO3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpl1258, lpg1296, DSM 7513 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=91891 Legionella pneumophila subsp. pneumophila])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oo3 OCA], [http://pdbe.org/2oo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2oo3 RCSB], [http://www.ebi.ac.uk/pdbsum/2oo3 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2oo3 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oo3 OCA], [https://pdbe.org/2oo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oo3 RCSB], [https://www.ebi.ac.uk/pdbsum/2oo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oo3 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2oo3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q5ZVZ2_LEGPH Q5ZVZ2_LEGPH]] Specifically methylates the adenine in position 2030 of 23S rRNA.[HAMAP-Rule:MF_00934]  
[https://www.uniprot.org/uniprot/Q5ZVZ2_LEGPH Q5ZVZ2_LEGPH] Specifically methylates the adenine in position 2030 of 23S rRNA.[HAMAP-Rule:MF_00934]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oo/2oo3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oo/2oo3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oo3 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Legionella pneumophila subsp. pneumophila]]
[[Category: Legionella pneumophila subsp. pneumophila]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Atwell, S]]
[[Category: Atwell S]]
[[Category: Bain, K T]]
[[Category: Bain KT]]
[[Category: Bonanno, J B]]
[[Category: Bonanno JB]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Freeman, J]]
[[Category: Freeman J]]
[[Category: Structural genomic]]
[[Category: Ozyurt S]]
[[Category: Ozyurt, S]]
[[Category: Reyes C]]
[[Category: Reyes, C]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: Slocombe A]]
[[Category: Slocombe, A]]
[[Category: Smyth L]]
[[Category: Smyth, L]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]

Latest revision as of 03:21, 28 December 2023

Crystal structure of protein LPL1258 from Legionella pneumophila str. Philadelphia 1, Pfam DUF519Crystal structure of protein LPL1258 from Legionella pneumophila str. Philadelphia 1, Pfam DUF519

Structural highlights

2oo3 is a 1 chain structure with sequence from Legionella pneumophila subsp. pneumophila. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

Q5ZVZ2_LEGPH Specifically methylates the adenine in position 2030 of 23S rRNA.[HAMAP-Rule:MF_00934]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2oo3, resolution 2.00Å

Drag the structure with the mouse to rotate

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OCA