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==Crystal structure of molybdopterin converting factor subunit 2 (aq_2181) from aquifex aeolicus VF5== | |||
<StructureSection load='2omd' size='340' side='right'caption='[[2omd]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2omd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OMD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
== | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
[[2omd]] is a 2 chain structure with sequence from [ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2omd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2omd OCA], [https://pdbe.org/2omd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2omd RCSB], [https://www.ebi.ac.uk/pdbsum/2omd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2omd ProSAT], [https://www.topsan.org/Proteins/RSGI/2omd TOPSAN]</span></td></tr> | ||
[[ | </table> | ||
[[ | == Function == | ||
[[ | [https://www.uniprot.org/uniprot/MOAE_AQUAE MOAE_AQUAE] Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity). | ||
[[ | == Evolutionary Conservation == | ||
[ | [[Image:Consurf_key_small.gif|200px|right]] | ||
[[ | Check<jmol> | ||
[ | <jmolCheckbox> | ||
[ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/2omd_consurf.spt"</scriptWhenChecked> | ||
[[Category: | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[[Category: | <text>to colour the structure by Evolutionary Conservation</text> | ||
[[Category: | </jmolCheckbox> | ||
[[Category: | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2omd ConSurf]. | ||
[[Category: | <div style="clear:both"></div> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Aquifex aeolicus VF5]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Agari Y]] | ||
[[Category: | [[Category: Ebihara A]] | ||
[[Category: | [[Category: Jeyakanthan J]] | ||
[[Category: Kanaujia SP]] | |||
[[Category: Kuramitsu S]] | |||
[[Category: Sekar K]] | |||
[[Category: Shinkai A]] | |||
[[Category: Shiro Y]] | |||
[[Category: Vasuki Ranjani C]] | |||
[[Category: Yokoyama S]] |
Latest revision as of 03:20, 28 December 2023
Crystal structure of molybdopterin converting factor subunit 2 (aq_2181) from aquifex aeolicus VF5Crystal structure of molybdopterin converting factor subunit 2 (aq_2181) from aquifex aeolicus VF5
Structural highlights
FunctionMOAE_AQUAE Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity). Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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