2nnt: Difference between revisions
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==General structural motifs of amyloid protofilaments== | ==General structural motifs of amyloid protofilaments== | ||
<StructureSection load='2nnt' size='340' side='right'caption='[[2nnt | <StructureSection load='2nnt' size='340' side='right'caption='[[2nnt]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2nnt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2nnt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NNT FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nnt OCA], [https://pdbe.org/2nnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nnt RCSB], [https://www.ebi.ac.uk/pdbsum/2nnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nnt ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nnt OCA], [https://pdbe.org/2nnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nnt RCSB], [https://www.ebi.ac.uk/pdbsum/2nnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nnt ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Becker | [[Category: Becker J]] | ||
[[Category: Berriman | [[Category: Berriman J]] | ||
[[Category: Ferguson | [[Category: Ferguson N]] | ||
[[Category: Fersht | [[Category: Fersht AR]] | ||
[[Category: Flinders | [[Category: Flinders J]] | ||
[[Category: Krause | [[Category: Krause G]] | ||
[[Category: Oschkinat | [[Category: Oschkinat H]] | ||
[[Category: Petrovich | [[Category: Petrovich M]] | ||
[[Category: Sharpe | [[Category: Sharpe TD]] | ||
[[Category: Tidow | [[Category: Tidow H]] | ||
[[Category: Tremmel | [[Category: Tremmel S]] | ||