1vji: Difference between revisions

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[[Image:1vji.gif|left|200px]]


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==Gene Product of At1g76680 from Arabidopsis thaliana==
The line below this paragraph, containing "STRUCTURE_1vji", creates the "Structure Box" on the page.
<StructureSection load='1vji' size='340' side='right'caption='[[1vji]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1vji]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VJI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.003&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
{{STRUCTURE_1vji| PDB=1vji |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vji OCA], [https://pdbe.org/1vji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vji RCSB], [https://www.ebi.ac.uk/pdbsum/1vji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vji ProSAT], [https://www.topsan.org/Proteins/CESG/1vji TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OPR1_ARATH OPR1_ARATH] Specifically cleaves olefinic bonds in alpha,beta-unsaturated carbonyls and may be involved in detoxification or modification of these reactive compounds. May be involved in the biosynthesis or metabolism of oxylipin signaling molecules. In vitro, reduces 9R,13R-12-oxophyodienoic acid (9R,13R-OPDA) to 9R,13R-OPC-8:0, but only poorly 9S,13S-OPDA, the natural precursor of jasmonic acid. Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro and in vivo by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT).<ref>PMID:19605548</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vj/1vji_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vji ConSurf].
<div style="clear:both"></div>


'''Gene Product of At1g76680 from Arabidopsis thaliana'''
==See Also==
 
*[[12-oxophytodienoate reductase 3D structures|12-oxophytodienoate reductase 3D structures]]
 
== References ==
==About this Structure==
<references/>
1VJI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VJI OCA].
__TOC__
 
</StructureSection>
==Reference==
X-ray structure of Arabidopsis At1g77680, 12-oxophytodienoate reductase isoform 1., Fox BG, Malone TE, Johnson KA, Madson SE, Aceti D, Bingman CA, Blommel PG, Buchan B, Burns B, Cao J, Cornilescu C, Doreleijers J, Ellefson J, Frederick R, Geetha H, Hruby D, Jeon WB, Kimball T, Kunert J, Markley JL, Newman C, Olson A, Peterson FC, Phillips GN Jr, Primm J, Ramirez B, Rosenberg NS, Runnels M, Seder K, Shaw J, Smith DW, Sreenath H, Song J, Sussman MR, Thao S, Troestler D, Tyler E, Tyler R, Ulrich E, Vinarov D, Vojtik F, Volkman BF, Wesenberg G, Wrobel RL, Zhang J, Zhao Q, Zolnai Z, Proteins. 2005 Oct 1;61(1):206-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16080145 16080145]
[[Category: Arabidopsis thaliana]]
[[Category: Single protein]]
[[Category: Bingman, C A.]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
[[Category: Johnson, K A.]]
[[Category: Jr., G N.Phillips.]]
[[Category: Smith, D W.]]
[[Category: Wesenberg, G E.]]
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Center for eukaryotic structural genomic]]
[[Category: Large Structures]]
[[Category: Cesg]]
[[Category: Bingman CA]]
[[Category: Plant protein]]
[[Category: Johnson KA]]
[[Category: Protein structure initiative]]
[[Category: Phillips Jr GN]]
[[Category: Structural genomic]]
[[Category: Smith DW]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 12:36:12 2008''
[[Category: Wesenberg GE]]

Latest revision as of 03:04, 28 December 2023

Gene Product of At1g76680 from Arabidopsis thalianaGene Product of At1g76680 from Arabidopsis thaliana

Structural highlights

1vji is a 1 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.003Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

OPR1_ARATH Specifically cleaves olefinic bonds in alpha,beta-unsaturated carbonyls and may be involved in detoxification or modification of these reactive compounds. May be involved in the biosynthesis or metabolism of oxylipin signaling molecules. In vitro, reduces 9R,13R-12-oxophyodienoic acid (9R,13R-OPDA) to 9R,13R-OPC-8:0, but only poorly 9S,13S-OPDA, the natural precursor of jasmonic acid. Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro and in vivo by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT).[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Beynon ER, Symons ZC, Jackson RG, Lorenz A, Rylott EL, Bruce NC. The role of oxophytodienoate reductases in the detoxification of the explosive 2,4,6-trinitrotoluene by Arabidopsis. Plant Physiol. 2009 Sep;151(1):253-61. doi: 10.1104/pp.109.141598. Epub 2009 Jul , 15. PMID:19605548 doi:http://dx.doi.org/10.1104/pp.109.141598

1vji, resolution 2.00Å

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