1v5u: Difference between revisions

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-{{Seed}}
-[[Image:1v5u.png|left|200px]]
-<!--
+==Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse==
-The line below this paragraph, containing "STRUCTURE_1v5u", creates the "Structure Box" on the page.
+<StructureSection load='1v5u' size='340' side='right'caption='[[1v5u]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1v5u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5U FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5u OCA], [https://pdbe.org/1v5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5u RCSB], [https://www.ebi.ac.uk/pdbsum/1v5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5u ProSAT], [https://www.topsan.org/Proteins/RSGI/1v5u TOPSAN]</span></td></tr>
-{{STRUCTURE_1v5u|  PDB=1v5u  |  SCENE=  }}
+</table>
+== Function ==
-===Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse===
+[https://www.uniprot.org/uniprot/MTMR5_MOUSE MTMR5_MOUSE] Acts as an adapter for the phosphatase MTMR2 to regulate MTMR2 catalytic activity and subcellular location. May function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts.[UniProtKB:O95248]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
-==About this Structure==
+Check<jmol>
-V5U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5U OCA].
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5u_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5u ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Single protein]]
+[[Category: Inoue M]]
-[[Category: Inoue, M.]]
+[[Category: Kigawa T]]
-[[Category: Kigawa, T.]]
+[[Category: Koshiba S]]
-[[Category: Koshiba, S.]]
+[[Category: Li H]]
-[[Category: Li, H.]]
+[[Category: Yokoyama S]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
-[[Category: Yokoyama, S.]]
-[[Category: Mtmr5]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Sbf1]]
-[[Category: Structural genomic]]
-[[Category: The pleckstrin homology domain]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Sep 28 21:19:36 2008''