1ujy: Difference between revisions

<StructureSection load='1ujy' size='340' side='right'caption='[[1ujy]]' scene=''>

<table><tr><td colspan='2'>[[1ujy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UJY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UJY FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ujy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ujy OCA], [https://pdbe.org/1ujy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ujy RCSB], [https://www.ebi.ac.uk/pdbsum/1ujy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ujy ProSAT], [https://www.topsan.org/Proteins/RSGI/1ujy TOPSAN]</span></td></tr>

[https://www.uniprot.org/uniprot/ARHG6_HUMAN ARHG6_HUMAN] Defects in ARHGEF6 are the cause of mental retardation X-linked type 46 (MRX46) [MIM:[https://omim.org/entry/300436 300436]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.<ref>PMID:11017088</ref>  

[https://www.uniprot.org/uniprot/ARHG6_HUMAN ARHG6_HUMAN] Acts as a RAC1 guanine nucleotide exchange factor (GEF).

     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uj/1ujy_consurf.spt"</scriptWhenChecked>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ujy ConSurf].

*[[Rho guanine nucleotide exchange factor 3D structures|Rho guanine nucleotide exchange factor 3D structures]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Aoki M]]

[[Category: He F]]

[[Category: Hirota H]]

[[Category: Inoue M]]

[[Category: Kigawa T]]

[[Category: Kikuno R]]

[[Category: Kobayashi N]]

[[Category: Koshiba S]]

[[Category: Matsuda T]]

[[Category: Matsuo Y]]

[[Category: Muto Y]]

[[Category: Nagase T]]

[[Category: Nagayama M]]

[[Category: Ohara O]]

[[Category: Osanai T]]

[[Category: Seki E]]

[[Category: Shirouzu M]]

[[Category: Tanaka A]]

[[Category: Terada T]]

[[Category: Uda H]]

[[Category: Yabuki T]]

[[Category: Yokoyama S]]

[[Category: Yoshida M]]