1uf7: Difference between revisions

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-[[Image:1uf7.gif|left|200px]]
- {{Structure
+==Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-valine==
-|PDB= 1uf7 |SIZE=350|CAPTION= <scene name='initialview01'>1uf7</scene>, resolution 1.90&Aring;
+<StructureSection load='1uf7' size='340' side='right'caption='[[1uf7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=CDV:3-METHYL-2-UREIDO-BUTYRIC ACID'>CDV</scene>
+<table><tr><td colspan='2'>[[1uf7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UF7 FirstGlance]. <br>
-|ACTIVITY= [http://en.wikipedia.org/wiki/N-carbamoyl-D-amino_acid_hydrolase N-carbamoyl-D-amino acid hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.77 3.5.1.77]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-|GENE=
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDV:3-METHYL-2-UREIDO-BUTYRIC+ACID'>CDV</scene></td></tr>
-}}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uf7 OCA], [https://pdbe.org/1uf7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uf7 RCSB], [https://www.ebi.ac.uk/pdbsum/1uf7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uf7 ProSAT]</span></td></tr>
+</table>
-'''Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-valine'''
+== Function ==
+[https://www.uniprot.org/uniprot/DCAS_AGRSK DCAS_AGRSK] The enzyme catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. Industrial production of beta-lactam antibiotics is now being developed using this enzyme.
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-UF7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF7 OCA].
+Check<jmol>
-[[Category: Agrobacterium sp.]]
+  <jmolCheckbox>
-[[Category: N-carbamoyl-D-amino acid hydrolase]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1uf7_consurf.spt"</scriptWhenChecked>
-[[Category: Single protein]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: Aoki, M.]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Hashimoto, H.]]
+  </jmolCheckbox>
-[[Category: Ikenaka, Y.]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uf7 ConSurf].
-[[Category: Morikawa, H.]]
+<div style="clear:both"></div>
-[[Category: Nakai, T.]]
+__TOC__
-[[Category: Sato, M.]]
+</StructureSection>
-[[Category: Shimizu, T.]]
+[[Category: Agrobacterium sp]]
-[[Category: Takahashi, S.]]
+[[Category: Large Structures]]
-[[Category: CDV]]
+[[Category: Aoki M]]
-[[Category: d-amino acid]]
+[[Category: Hashimoto H]]
-[[Category: hydrolase]]
+[[Category: Ikenaka Y]]
-[[Category: n-carbamyl-d-amino acid amidohydrolase]]
+[[Category: Morikawa H]]
-[[Category: n-carbamyl-d-valine]]
+[[Category: Nakai T]]
+[[Category: Sato M]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:31:17 2008''
+[[Category: Shimizu T]]
+[[Category: Takahashi S]]