1ue9: Difference between revisions

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-[[Image:1ue9.jpg|left|200px]]
- {{Structure
+==Solution structure of the fourth SH3 domain of human intersectin 2 (KIAA1256)==
-|PDB= 1ue9 |SIZE=350|CAPTION= <scene name='initialview01'>1ue9</scene>
+<StructureSection load='1ue9' size='340' side='right'caption='[[1ue9]]' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[1ue9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UE9 FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-|GENE= Kazusa cDNA hh15293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ue9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ue9 OCA], [https://pdbe.org/1ue9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ue9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ue9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ue9 ProSAT], [https://www.topsan.org/Proteins/RSGI/1ue9 TOPSAN]</span></td></tr>
-|DOMAIN=
+</table>
-|RELATEDENTRY=
+== Function ==
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ue9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ue9 OCA], [http://www.ebi.ac.uk/pdbsum/1ue9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ue9 RCSB]</span>
+[https://www.uniprot.org/uniprot/ITSN2_HUMAN ITSN2_HUMAN] Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR).<ref>PMID:19458185</ref> <ref>PMID:22648170</ref>
-}}
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ue/1ue9_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ue9 ConSurf].
+<div style="clear:both"></div>
-'''Solution structure of the fourth SH3 domain of human intersectin 2 (KIAA1256)'''
+==See Also==
+*[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]]
+*[[Intersectin|Intersectin]]
-==About this Structure==
+== References ==
-UE9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UE9 OCA].
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Inoue, M.]]
+[[Category: Inoue M]]
-[[Category: Kigawa, T.]]
+[[Category: Kigawa T]]
-[[Category: Kobayashi, N.]]
+[[Category: Kobayashi N]]
-[[Category: Koshiba, S.]]
+[[Category: Koshiba S]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Tochio N]]
-[[Category: Tochio, N.]]
+[[Category: Yokoyama S]]
-[[Category: Yokoyama, S.]]
-[[Category: beta barrel]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: sh3 domain]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:09:08 2008''