1j3t: Difference between revisions

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 ==Solution structure of the second SH3 domain of human intersectin 2 (KIAA1256)==
-<StructureSection load='1j3t' size='340' side='right' caption='[[1j3t]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='1j3t' size='340' side='right'caption='[[1j3t]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1j3t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J3T FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1j3t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J3T FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Kazusa cDNA hh15293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j3t RCSB], [http://www.ebi.ac.uk/pdbsum/1j3t PDBsum], [http://www.topsan.org/Proteins/RSGI/1j3t TOPSAN]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3t OCA], [https://pdbe.org/1j3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j3t RCSB], [https://www.ebi.ac.uk/pdbsum/1j3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j3t ProSAT], [https://www.topsan.org/Proteins/RSGI/1j3t TOPSAN]</span></td></tr>
-<table>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ITSN2_HUMAN ITSN2_HUMAN] Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR).<ref>PMID:19458185</ref> <ref>PMID:22648170</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j3/1j3t_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j3/1j3t_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j3t ConSurf].
 <div style="clear:both"></div>
+==See Also==
+*[[Intersectin|Intersectin]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Inoue, M.]]
+[[Category: Large Structures]]
-[[Category: Kigawa, T.]]
+[[Category: Inoue M]]
-[[Category: Kobayashi, N.]]
+[[Category: Kigawa T]]
-[[Category: Koshiba, S.]]
+[[Category: Kobayashi N]]
-[[Category: Nameki, N.]]
+[[Category: Koshiba S]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Nameki N]]
-[[Category: Tochio, N.]]
+[[Category: Tochio N]]
-[[Category: Yokoyama, S.]]
+[[Category: Yokoyama S]]
-[[Category: Beta barrel]]
-[[Category: Endocytosis-exocytosis complex]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Sh3 domain]]
-[[Category: Structural genomic]]