1j2g: Difference between revisions

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-[[Image:1j2g.gif|left|200px]]
- {{Structure
+==Crystal structure of Urate oxidase from Bacillus SP. TB-90 co-crystallized with 8-Azaxanthine==
-|PDB= 1j2g |SIZE=350|CAPTION= <scene name='initialview01'>1j2g</scene>, resolution 2.20&Aring;
+<StructureSection load='1j2g' size='340' side='right'caption='[[1j2g]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
+<table><tr><td colspan='2'>[[1j2g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._TB-90 Bacillus sp. TB-90]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J2G FirstGlance]. <br>
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Urate_oxidase Urate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.3.3 1.7.3.3] </span>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-|GENE=
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-|DOMAIN=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j2g OCA], [https://pdbe.org/1j2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j2g RCSB], [https://www.ebi.ac.uk/pdbsum/1j2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j2g ProSAT]</span></td></tr>
-|RELATEDENTRY=[[1uox|1UOX]]
+</table>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j2g OCA], [http://www.ebi.ac.uk/pdbsum/1j2g PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1j2g RCSB]</span>
+== Function ==
-}}
+[https://www.uniprot.org/uniprot/PUCL_BACSB PUCL_BACSB] Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j2/1j2g_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j2g ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of Urate oxidase from Bacillus SP. TB-90 co-crystallized with 8-Azaxanthine'''
+==See Also==
+*[[Urate oxidase 3D structures|Urate oxidase 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-J2G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J2G OCA].
+[[Category: Bacillus sp. TB-90]]
-[[Category: Bacillus sp.]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Hibi T]]
-[[Category: Urate oxidase]]
+[[Category: Nago T]]
-[[Category: Hibi, T.]]
+[[Category: Nishiya Y]]
-[[Category: Nago, T.]]
+[[Category: Oda J]]
-[[Category: Nishiya, Y.]]
-[[Category: Oda, J.]]
-[[Category: purine]]
-[[Category: t-fold barrel]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:27:58 2008''