1co0: Difference between revisions

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-{{Seed}}
-[[Image:1co0.png|left|200px]]
-<!--
+==NMR STUDY OF TRP REPRESSOR-MTR OPERATOR DNA COMPLEX==
-The line below this paragraph, containing "STRUCTURE_1co0", creates the "Structure Box" on the page.
+<StructureSection load='1co0' size='340' side='right'caption='[[1co0]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1co0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CO0 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr>
-{{STRUCTURE_1co0|  PDB=1co0  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1co0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1co0 OCA], [https://pdbe.org/1co0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1co0 RCSB], [https://www.ebi.ac.uk/pdbsum/1co0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1co0 ProSAT]</span></td></tr>
+</table>
-===NMR STUDY OF TRP REPRESSOR-MTR OPERATOR DNA COMPLEX===
+== Function ==
+[https://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-CO0 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CO0 OCA].
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/1co0_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1co0 ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Brocchieri, L.]]
+[[Category: Large Structures]]
-[[Category: Jardetzky, O.]]
+[[Category: Brocchieri L]]
-[[Category: Zhou, G P.]]
+[[Category: Jardetzky O]]
-[[Category: Dna]]
+[[Category: Zhou GP]]
-[[Category: Dna-binding]]
-[[Category: Peptide]]
-[[Category: Repressor]]
-[[Category: Transcription regulation]]
-[[Category: Trp]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:53:58 2009''