1cjd: Difference between revisions

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-{{Seed}}
-[[Image:1cjd.png|left|200px]]
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+==THE BACTERIOPHAGE PRD1 COAT PROTEIN, P3, IS STRUCTURALLY SIMILAR TO HUMAN ADENOVIRUS HEXON==
-The line below this paragraph, containing "STRUCTURE_1cjd", creates the "Structure Box" on the page.
+<StructureSection load='1cjd' size='340' side='right'caption='[[1cjd]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1cjd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_PRD1 Enterobacteria phage PRD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CJD FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cjd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cjd OCA], [https://pdbe.org/1cjd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cjd RCSB], [https://www.ebi.ac.uk/pdbsum/1cjd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cjd ProSAT]</span></td></tr>
-{{STRUCTURE_1cjd|  PDB=1cjd  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CAPSD_BPPRD CAPSD_BPPRD] Major capsid protein self-assembles to form an icosahedral capsid with a pseudo T=25 symmetry, about 66 nm in diameter, and consisting of 240 capsid proteins trimers. The capsid encapsulates an inner membrane and the genomic dsDNA genome. The major coat protein P3 and two assembly factors (P10 and P17) are needed during the assembly of the virus particle inside the host cell, when the capsid protein multimers are capable of enclosing the host-derived membrane, containing the virus-encoded membrane-associated proteins.
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The unusual bacteriophage PRD1 features a membrane beneath its icosahedral protein coat. The crystal structure of the major coat protein, P3, at 1.85 A resolution reveals a molecule with three interlocking subunits, each with two eight-stranded viral jelly rolls normal to the viral capsid, and putative membrane-interacting regions. Surprisingly, the P3 molecule closely resembles hexon, the equivalent protein in human adenovirus. Both viruses also have similar overall architecture, with identical capsid lattices and attachment proteins at their vertices. Although these two dsDNA viruses infect hosts from very different kingdoms, their striking similarities, from major coat protein through capsid architecture, strongly suggest their evolutionary relationship.
-===THE BACTERIOPHAGE PRD1 COAT PROTEIN, P3, IS STRUCTURALLY SIMILAR TO HUMAN ADENOVIRUS HEXON===
+Viral evolution revealed by bacteriophage PRD1 and human adenovirus coat protein structures.,Benson SD, Bamford JK, Bamford DH, Burnett RM Cell. 1999 Sep 17;98(6):825-33. PMID:10499799<ref>PMID:10499799</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_10499799}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 1cjd" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 10499799 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_10499799}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Enterobacteria phage PRD1]]
-CJD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_prd1 Enterobacteria phage prd1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJD OCA].
+[[Category: Large Structures]]
+[[Category: Bamford DH]]
-==Reference==
+[[Category: Bamford JKH]]
-Viral evolution revealed by bacteriophage PRD1 and human adenovirus coat protein structures., Benson SD, Bamford JK, Bamford DH, Burnett RM, Cell. 1999 Sep 17;98(6):825-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10499799 10499799]
+[[Category: Benson SD]]
-[[Category: Enterobacteria phage prd1]]
+[[Category: Burnett RM]]
-[[Category: Single protein]]
-[[Category: Bamford, D H.]]
-[[Category: Bamford, J K.H.]]
-[[Category: Benson, S D.]]
-[[Category: Burnett, R M.]]
-[[Category: Bacteriophage prd1]]
-[[Category: Coat protein]]
-[[Category: Jelly roll]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:49:51 2008''