1c76: Difference between revisions

New page: left|200px<br /><applet load="1c76" size="450" color="white" frame="true" align="right" spinBox="true" caption="1c76, resolution 2.25Å" /> '''STAPHYLOKINASE (SAK)...
 
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[[Image:1c76.gif|left|200px]]<br /><applet load="1c76" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1c76, resolution 2.25&Aring;" />
'''STAPHYLOKINASE (SAK) MONOMER'''<br />


==About this Structure==
==STAPHYLOKINASE (SAK) MONOMER==
1C76 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Active as [http://en.wikipedia.org/wiki/Aureolysin Aureolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.29 3.4.24.29] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1C76 OCA].  
<StructureSection load='1c76' size='340' side='right'caption='[[1c76]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
[[Category: Aureolysin]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1c76]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C76 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c76 OCA], [https://pdbe.org/1c76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c76 RCSB], [https://www.ebi.ac.uk/pdbsum/1c76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c76 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SAK_STAAU SAK_STAAU] Potent plasminogen activator that converts plasminogen into plasmin. It forms a 1:1 complex with plasmin, which in turn activates other plasminogen molecules.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/1c76_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c76 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Bartlam, M.]]
[[Category: Bartlam M]]
[[Category: Chen, Y.]]
[[Category: Chen Y]]
[[Category: Ding, Y.]]
[[Category: Ding Y]]
[[Category: Jiang, F.]]
[[Category: Jiang F]]
[[Category: Liu, Y.]]
[[Category: Liu Y]]
[[Category: Rao, Z.]]
[[Category: Rao Z]]
[[Category: Song, H.]]
[[Category: Song H]]
[[Category: Zhang, X.]]
[[Category: Zhang X]]
[[Category: beta-grasp family]]
 
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