1bu9: Difference between revisions

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==SOLUTION STRUCTURE OF P18-INK4C, 21 STRUCTURES==
==SOLUTION STRUCTURE OF P18-INK4C, 21 STRUCTURES==
<StructureSection load='1bu9' size='340' side='right' caption='[[1bu9]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
<StructureSection load='1bu9' size='340' side='right'caption='[[1bu9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1bu9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BU9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1bu9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BU9 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bu9 OCA], [http://pdbe.org/1bu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bu9 RCSB], [http://www.ebi.ac.uk/pdbsum/1bu9 PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bu9 OCA], [https://pdbe.org/1bu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bu9 RCSB], [https://www.ebi.ac.uk/pdbsum/1bu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bu9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CDN2C_HUMAN CDN2C_HUMAN]] Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.  
[https://www.uniprot.org/uniprot/CDN2C_HUMAN CDN2C_HUMAN] Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bu/1bu9_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bu/1bu9_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Byeon, I J.L]]
[[Category: Large Structures]]
[[Category: Li, J]]
[[Category: Byeon I-JL]]
[[Category: Tsai, M D]]
[[Category: Li J]]
[[Category: Cell cycle inhibitor]]
[[Category: Tsai M-D]]
[[Category: Cyclin-dependent kinase]]
[[Category: Hormone-growth factor complex]]
[[Category: P18ink4c]]
[[Category: Suppressor]]
[[Category: Tumor]]

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