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Toll-like Receptor 3D structures: Difference between revisions

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|


*Toll-like receptor 1; Domains – TIR 625-785; ligand-binding (LBD) 22-703; transmembrane 698-730
*Toll-like receptor 1; Domains – Transmembrane+juxtamembrane 581-629; TIR 625-785; ligand-binding (LBD) 22-703; transmembrane 698-730


**[[1fyv]] – hTLR1 TIR domain – human<br />
**[[1fyv]] – hTLR1 TIR domain – human<br />
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*Toll-like receptor 2
*Toll-like receptor 2


**[[1fyw]] – hTLR2 TIR domain<br />
**[[8ar0]], [[8ar1]], [[8ar2]], [[8ar3]] – hTLR2 transmembrane+juxtamembrane domain – NMR<br />
**[[1fyw]], [[7nux]], [[7nux]] – hTLR2 TIR domain<br />
**[[7nt7]] – hTLR1 TIR domain – NMR<br />
**[[1fyx]], [[1o77]] - hTLR2 TIR domain (mutant) <br />
**[[1fyx]], [[1o77]] - hTLR2 TIR domain (mutant) <br />
**[[2z80]] – hTLR2/VLRB.61<br />
**[[2z80]] – hTLR2/VLRB.61<br />
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**[[2mk9]], [[2mka]] – hTLR3 transmembrane domain - NMR <br />
**[[2mk9]], [[2mka]] – hTLR3 transmembrane domain - NMR <br />
**[[3ulv]], [[3ulu]], [[5gs0]] – hTLR3 LBD + antibody<br />
**[[3ulv]], [[3ulu]], [[5gs0]] – hTLR3 LBD + antibody<br />
**[[7c76]] – hTLR3 + UNC93B1 – Cryo EM<br />
**[[7wm4]], [[7wv3]], [[7wv4]], [[7wv5]], [[7wvj]] – hTLR3 LBD + RNA – Cryo EM<br />
**[[7wve]] – hTLR3 LBD (mutant) + RNA – Cryo EM<br />
**[[7wvf]] – hTLR3 LBD + antibody + RNA – Cryo EM<br />
**[[7c77]] – mTLR3 + UNC93B1 – Cryo EM<br />
**[[7da7]], [[7das]] – mTLR3 LBD + RNA – Cryo EM<br />
**[[3cig]] – mTLR3 LBD<br />
**[[3cig]] – mTLR3 LBD<br />
**[[3ciy]] - mTLR3 LBD + RNA<br />
**[[3ciy]] - mTLR3 LBD + RNA<br />
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**[[3ula]] - hTLR4/VLRB.61 + lymphocyte antigen 96<br />
**[[3ula]] - hTLR4/VLRB.61 + lymphocyte antigen 96<br />
**[[2z64]], [[2z65]], [[5ijc]], [[5ijd]], [[3vq1]], [[3vq2]] – mTLR4 LBD + lymphocyte antigen 96<br />
**[[2z64]], [[2z65]], [[5ijc]], [[5ijd]], [[3vq1]], [[3vq2]] – mTLR4 LBD + lymphocyte antigen 96<br />
**[[7mlm]] - mTLR4/VLRB.61 + lymphocyte antigen 96 + sulfatide<br />


*Toll-like receptor 5
*Toll-like receptor 5


**[[3j0a]] – hTLR5<br />
**[[3j0a]] – hTLR5<br />
*Toll-like receptor 5A
**[[7b1b]], [[7b1c]], [[7b1d]] – TLR5A + Spz1C – yellow fever mosquito - Cryo EM<br />


*Toll-like receptor 5B
*Toll-like receptor 5B
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*Toll-like receptor 7
*Toll-like receptor 7


**[[7cyn]] – hTLR7 + UNC93B1 – Cryo EM<br />
**[[5gmf]] – moTLR7 + guanosine + poly-U - monkey <br />
**[[5gmf]] – moTLR7 + guanosine + poly-U - monkey <br />
**[[5gmg]] – moTLR7 + loxoribine + poly-U  <br />
**[[5gmg]] – moTLR7 + loxoribine + poly-U  <br />
**[[5gmh]] – moTLR7 + resiquimod + poly-U  <br />
**[[5gmh]] – moTLR7 + resiquimod + poly-U  <br />
**[[5zsl]], [[5zsm]], [[5zsn]] – moTLR7 (mutant) + RNA <br />
**[[5zsg]], [[5zsh]], [[5zsi]], [[5zsj]], [[6lvz]], [[6lw1]], [[7ytp]] – moTLR7 (mutant) + inhibitor<br />
**[[6lvx]], [[6lvy]], [[6lw0]] – moTLR7 (mutant) + antagonist<br />
**[[6if5]] – moTLR7 (mutant) + cGMP<br />
**[[5zsf]] – moTLR7 (mutant) + drug<br />
**[[5zsa]], [[5zsb]], [[5zsd]], [[5zse]] – moTLR7 (mutant) + RNA + inhibitort<br />


*Toll-like receptor 8
*Toll-like receptor 8


**[[3w3g]], [[5hdh]] – hTLR8 <br />
**[[3w3g]], [[5hdh]] – hTLR8 <br />
**[[3w3j]], [[3w3k]], [[3w3l]], [[3w3m]], [[3w3n]], [[3wn4]], [[5awa]], [[5awc]], [[5awb]], [[5awd]], [[4r6a]], [[4qbz]], [[4qc0]], [[5az5]] – hTLR8 + agonist<br />
**[[3w3j]], [[3w3k]], [[3w3l]], [[3w3m]], [[3w3n]], [[3wn4]], [[5awa]], [[5awc]], [[5awb]], [[5awd]], [[4r6a]], [[4qbz]], [[4qc0]], [[5az5]], [[6v9u]], [[6wml]], [[6zjz]], [[7crf]], [[7r52]], [[7r53]], [[7r54]] – hTLR8 + agonist<br />
**[[6kya]], [[6ty5]], [[7rc9]], [[7ytx]], [[8pfi]] – hTLR8 + antagonist<br />
**[[4r07]], [[4r09]] – hTLR8 + ORN06 <br />
**[[4r07]], [[4r09]] – hTLR8 + ORN06 <br />
**[[4r08]] – hTLR8 + RNA <br />
**[[4r08]] – hTLR8 + RNA <br />
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**[[4z0c]] – mTLR13 + RNA <br />
**[[4z0c]] – mTLR13 + RNA <br />
*Toll-like receptor 15
**[[7ylf]], [[7ylg]] – TLR10 TIR domain - chicken<br />


  }}
  }}


[[Category:Topic Page]]
[[Category:Topic Page]]

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Michal Harel
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