484d: Difference between revisions

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==SOLUTION STRUCTURE OF HIV-1 REV PEPTIDE-RNA APTAMER COMPLEX==
==SOLUTION STRUCTURE OF HIV-1 REV PEPTIDE-RNA APTAMER COMPLEX==
<StructureSection load='484d' size='340' side='right' caption='[[484d]], [[NMR_Ensembles_of_Models | 22 NMR models]]' scene=''>
<StructureSection load='484d' size='340' side='right'caption='[[484d]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[484d]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=484D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=484D FirstGlance]. <br>
<table><tr><td colspan='2'>[[484d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=484D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=484D FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=484d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=484d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=484d RCSB], [http://www.ebi.ac.uk/pdbsum/484d PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=484d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=484d OCA], [https://pdbe.org/484d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=484d RCSB], [https://www.ebi.ac.uk/pdbsum/484d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=484d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q79994_9HIV1 Q79994_9HIV1] Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.[RuleBase:RU364044]
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
<div class="pdbe-citations 484d" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ellington, A]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Frederick, R]]
[[Category: Large Structures]]
[[Category: Gorin, A A]]
[[Category: Ellington A]]
[[Category: Hu, W]]
[[Category: Frederick R]]
[[Category: Majumdar, A]]
[[Category: Gorin AA]]
[[Category: Mclendon, G]]
[[Category: Hu W]]
[[Category: Patel, D J]]
[[Category: Majumdar A]]
[[Category: Xu, W]]
[[Category: Mclendon G]]
[[Category: Ye, X]]
[[Category: Patel DJ]]
[[Category: Adaptive-binding]]
[[Category: Xu W]]
[[Category: Bound peptide secondary structure]]
[[Category: Ye X]]
[[Category: Hiv-1 rev peptide]]
[[Category: Peptide- binding rna]]
[[Category: Rna aptamer]]
[[Category: Rna binding protein-rna complex]]
[[Category: Tertiary architecture]]

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