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==Solution structure and cell selectivity of Piscidin 1 and its analogues==
==Solution structure and cell selectivity of Piscidin 1 and its analogues==
<StructureSection load='2ojm' size='340' side='right' caption='[[2ojm]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ojm' size='340' side='right'caption='[[2ojm]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ojm]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OJM FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ojm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Morone_saxatilis Morone saxatilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OJM FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ojn|2ojn]], [[2ojo|2ojo]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ojm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ojm OCA], [http://pdbe.org/2ojm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ojm RCSB], [http://www.ebi.ac.uk/pdbsum/2ojm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ojm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ojm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ojm OCA], [https://pdbe.org/2ojm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ojm RCSB], [https://www.ebi.ac.uk/pdbsum/2ojm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ojm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MORO_MORSA MORO_MORSA]] Exhibits broad spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria as well as against a variety of fungi. Has hemolytic activity. Seems to disrupt the membranes by adopting an alpha helical conformation and forming toroidal pores.<ref>PMID:11713517</ref> <ref>PMID:17253775</ref>
[https://www.uniprot.org/uniprot/MORO_MORSA MORO_MORSA] Exhibits broad spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria as well as against a variety of fungi. Has hemolytic activity. Seems to disrupt the membranes by adopting an alpha helical conformation and forming toroidal pores.<ref>PMID:11713517</ref> <ref>PMID:17253775</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Kim, Y]]
[[Category: Large Structures]]
[[Category: Kim, Y K]]
[[Category: Morone saxatilis]]
[[Category: Lee, S A]]
[[Category: Kim Y]]
[[Category: Antimicrobial peptide]]
[[Category: Kim YK]]
[[Category: Antimicrobial protein]]
[[Category: Lee SA]]
[[Category: Membrane]]
[[Category: Piscidin 1]]
[[Category: Proline]]

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