4ucc: Difference between revisions
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==N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M76== | ==N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M76== | ||
<StructureSection load='4ucc' size='340' side='right' caption='[[4ucc]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='4ucc' size='340' side='right'caption='[[4ucc]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ucc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCC OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4ucc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus_A2 Human respiratory syncytial virus A2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UCC FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZKW:1-[(2,4-DICHLOROPHENYL)METHYL]PYRAZOLE-3,5-DICARBOXYLIC+ACID'>ZKW</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ucc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ucc OCA], [https://pdbe.org/4ucc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ucc RCSB], [https://www.ebi.ac.uk/pdbsum/4ucc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ucc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/NCAP_HRSVA NCAP_HRSVA] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.<ref>PMID:9299631</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4ucc" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4ucc" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Baron | [[Category: Human respiratory syncytial virus A2]] | ||
[[Category: Bontems | [[Category: Large Structures]] | ||
[[Category: Duquerroy | [[Category: Baron B]] | ||
[[Category: Eleouet | [[Category: Bontems F]] | ||
[[Category: England | [[Category: Duquerroy S]] | ||
[[Category: Galloux | [[Category: Eleouet J-F]] | ||
[[Category: Hoos | [[Category: England P]] | ||
[[Category: Ouizougun-Oubari | [[Category: Galloux M]] | ||
[[Category: Pereira | [[Category: Hoos S]] | ||
[[Category: Rey | [[Category: Ouizougun-Oubari M]] | ||
[[Category: Sizun | [[Category: Pereira N]] | ||
[[Category: Slama-Schwok | [[Category: Rey FA]] | ||
[[Category: Tarus | [[Category: Sizun C]] | ||
[[Category: Tortorici | [[Category: Slama-Schwok A]] | ||
[[Category: Tarus B]] | |||
[[Category: Tortorici M-A]] | |||