4d42: Difference between revisions

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==Crystal structure of S. aureus FabI in complex with NADP and 4-fluoro- 5-hexyl-2-phenoxyphenol==
==Crystal structure of S. aureus FabI in complex with NADP and 4-fluoro- 5-hexyl-2-phenoxyphenol==
<StructureSection load='4d42' size='340' side='right' caption='[[4d42]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
<StructureSection load='4d42' size='340' side='right'caption='[[4d42]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4d42]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D42 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D42 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4d42]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D42 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D42 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=W0I:4-FLUORO-5-HEXYL-2-PHENOXYPHENOL'>W0I</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d41|4d41]], [[4d43|4d43]], [[4d44|4d44]], [[4d45|4d45]], [[4d46|4d46]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=W0I:4-FLUORO-5-HEXYL-2-PHENOXYPHENOL'>W0I</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADPH,_B-specific) Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.10 1.3.1.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d42 OCA], [https://pdbe.org/4d42 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d42 RCSB], [https://www.ebi.ac.uk/pdbsum/4d42 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d42 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d42 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d42 RCSB], [http://www.ebi.ac.uk/pdbsum/4d42 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0J9X1Y0_STAAN A0A0J9X1Y0_STAAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4d42" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chang, A]]
[[Category: Large Structures]]
[[Category: Kisker, C]]
[[Category: Staphylococcus aureus subsp. aureus N315]]
[[Category: Schiebel, J]]
[[Category: Chang A]]
[[Category: Sotriffer, C A]]
[[Category: Kisker C]]
[[Category: Tonge, P J]]
[[Category: Schiebel J]]
[[Category: Fabi]]
[[Category: Sotriffer CA]]
[[Category: Fatty acid biosynthesis]]
[[Category: Tonge PJ]]
[[Category: Lipid synthesis]]
[[Category: Oxidoreductase]]
[[Category: Safabi]]
[[Category: Short-chain dehydrogenase/reductase superfamily]]

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