4d28: Difference between revisions

==Crystal structure of the kinase domain of CIPK24/SOS2==

<StructureSection load='4d28' size='340' side='right'caption='[[4d28]], [[Resolution|resolution]] 3.30&Aring;' scene=''>

<table><tr><td colspan='2'>[[4d28]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D28 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d28 OCA], [https://pdbe.org/4d28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d28 RCSB], [https://www.ebi.ac.uk/pdbsum/4d28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d28 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/CIPKO_ARATH CIPKO_ARATH] Involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Activates the vacuolar H(+)/Ca(2+) antiporter CAX1 and operates in synergy with CBL4/SOS3 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Phosphorylates CBL1, CBL4 and CBL10.<ref>PMID:10725350</ref> <ref>PMID:12034882</ref> <ref>PMID:14583601</ref> <ref>PMID:22253446</ref>  

[[Category: Arabidopsis thaliana]]

[[Category: Large Structures]]

[[Category: Albert A]]

[[Category: Chaves-Sanjuan A]]

[[Category: Gonzalez-Rubio JM]]

[[Category: Sanchez-Barrena MJ]]