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==Crystal structure of kynurenine formamidase from Bacillus anthracis complexed with 2-aminoacetophenone.==
==Crystal structure of kynurenine formamidase from Bacillus anthracis complexed with 2-aminoacetophenone.==
<StructureSection load='4cz1' size='340' side='right' caption='[[4cz1]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
<StructureSection load='4cz1' size='340' side='right'caption='[[4cz1]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cz1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_(strain_ames) Bacillus anthracis (strain ames)]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4coa 4coa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CZ1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cz1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4coa 4coa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CZ1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=VNJ:2-AMINOACETOPHENONE'>VNJ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4co9|4co9]], [[4cob|4cob]], [[4cog|4cog]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=VNJ:2-AMINOACETOPHENONE'>VNJ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KYNB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis (strain Ames)])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cz1 OCA], [https://pdbe.org/4cz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cz1 RCSB], [https://www.ebi.ac.uk/pdbsum/4cz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cz1 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arylformamidase Arylformamidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.9 3.5.1.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cz1 OCA], [http://pdbe.org/4cz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cz1 RCSB], [http://www.ebi.ac.uk/pdbsum/4cz1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cz1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KYNB_BACAN KYNB_BACAN]] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity).  
[https://www.uniprot.org/uniprot/KYNB_BACAN KYNB_BACAN] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity).
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arylformamidase]]
[[Category: Bacillus anthracis str. Ames]]
[[Category: Diaz-Saez, L]]
[[Category: Large Structures]]
[[Category: Hunter, W N]]
[[Category: Diaz-Saez L]]
[[Category: Srikannathasan, V]]
[[Category: Hunter WN]]
[[Category: Zoltner, M]]
[[Category: Srikannathasan V]]
[[Category: Hydrolase]]
[[Category: Zoltner M]]
[[Category: Tryptophan degradation pathway via anthranilate]]

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