4cst: Difference between revisions

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==Crystal structure of FimH in complex with 3'-Chloro-4'-(alpha-D-mannopyranosyloxy)-biphenyl-4-carbonitrile==
==Crystal structure of FimH in complex with 3'-Chloro-4'-(alpha-D-mannopyranosyloxy)-biphenyl-4-carbonitrile==
<StructureSection load='4cst' size='340' side='right' caption='[[4cst]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
<StructureSection load='4cst' size='340' side='right'caption='[[4cst]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cst]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CST FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cst]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CST FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CWK:3-CHLORO-4-(ALPHA-D-MANNOPYRANOSYLOXY)BIPHENYL-4-CARBONITRILE'>CWK</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4css|4css]], [[4csy|4csy]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CWK:3-CHLORO-4-(ALPHA-D-MANNOPYRANOSYLOXY)BIPHENYL-4-CARBONITRILE'>CWK</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cst OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cst RCSB], [http://www.ebi.ac.uk/pdbsum/4cst PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cst OCA], [https://pdbe.org/4cst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cst RCSB], [https://www.ebi.ac.uk/pdbsum/4cst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cst ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.  
[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4cst" style="background-color:#fffaf0;"></div>
==See Also==
*[[Adhesin 3D structures|Adhesin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Abgottspon, D]]
[[Category: Escherichia coli K-12]]
[[Category: Eris, D]]
[[Category: Large Structures]]
[[Category: Ernst, B]]
[[Category: Abgottspon D]]
[[Category: Hutter, A]]
[[Category: Eris D]]
[[Category: Jakob, R P]]
[[Category: Ernst B]]
[[Category: Jian, X]]
[[Category: Hutter A]]
[[Category: Kleeb, S]]
[[Category: Jakob RP]]
[[Category: Luedin, N]]
[[Category: Jian X]]
[[Category: Maier, T]]
[[Category: Kleeb S]]
[[Category: Mayer, K]]
[[Category: Luedin N]]
[[Category: Navarra, G]]
[[Category: Maier T]]
[[Category: Pang, L]]
[[Category: Mayer K]]
[[Category: Preston, R C]]
[[Category: Navarra G]]
[[Category: Rabbani, S]]
[[Category: Pang L]]
[[Category: Scharenberg, M]]
[[Category: Preston RC]]
[[Category: Schwardt, O]]
[[Category: Rabbani S]]
[[Category: Sharpe, T]]
[[Category: Scharenberg M]]
[[Category: Sigl, A]]
[[Category: Schwardt O]]
[[Category: Smiesko, M]]
[[Category: Sharpe T]]
[[Category: Zihlmann, P]]
[[Category: Sigl A]]
[[Category: Adhesin]]
[[Category: Smiesko M]]
[[Category: Fimh antagonist]]
[[Category: Zihlmann P]]
[[Category: Sugar binding protein]]
[[Category: Type i pili]]
[[Category: Upec]]
[[Category: Uti]]

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