4cqn: Difference between revisions

No edit summary
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Crystal structure of the E.coli LeuRS-tRNA complex with the non- cognate isoleucyl adenylate analogue==
==Crystal structure of the E.coli LeuRS-tRNA complex with the non- cognate isoleucyl adenylate analogue==
<StructureSection load='4cqn' size='340' side='right' caption='[[4cqn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4cqn' size='340' side='right'caption='[[4cqn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cqn]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CQN FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cqn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CQN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ILA:N-[ISOLEUCINYL]-N-[ADENOSYL]-DIAMINOSUFONE'>ILA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Leucine--tRNA_ligase Leucine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.4 6.1.1.4] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ILA:N-[ISOLEUCINYL]-N-[ADENOSYL]-DIAMINOSUFONE'>ILA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cqn RCSB], [http://www.ebi.ac.uk/pdbsum/4cqn PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cqn OCA], [https://pdbe.org/4cqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cqn RCSB], [https://www.ebi.ac.uk/pdbsum/4cqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cqn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYL_ECOLI SYL_ECOLI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 15: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4cqn" style="background-color:#fffaf0;"></div>
==See Also==
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Leucine--tRNA ligase]]
[[Category: Escherichia coli]]
[[Category: Cusack, S]]
[[Category: Escherichia coli K-12]]
[[Category: Cvetesic, N]]
[[Category: Large Structures]]
[[Category: Gruic-Sovulj, I]]
[[Category: Cusack S]]
[[Category: Haslaz, I]]
[[Category: Cvetesic N]]
[[Category: Palencia, A]]
[[Category: Gruic-Sovulj I]]
[[Category: Adaptive response and evolution]]
[[Category: Haslaz I]]
[[Category: Ligase]]
[[Category: Palencia A]]
[[Category: Ligase-rna complex]]
[[Category: Translational fidelity]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA